Antimicrobial Activities of Some Actinomycete Strains Isolated from the Sinai Egypt Soils

Document Type : Original Article

Authors

1 Plant Protection Department, Desert Research Center, Mataria, Cairo, Egypt

2 Botany and Microbiology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

3 Botany and Microbiology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt.

4 Plant Protection Department, Desert Research Center, Mataria, Cairo, Egypt.

Abstract

Seventy three pure actinomycete colonies were isolated
from 48 rhizospheric soil samples revealing different locations in Sinai. These
isolates were tested for their antimicrobial activities against Bacillus
subtilis
and Staphylococcus aureus as gram-positive bacteria, Escherichia
coli
and Pseudomonas aeruginosa as gram-negative bacteria, Candida
albicans
as an unicellular fungi and Aspergillus niger, Aspergillus
flavus
, Rhizoctonia solani and Fusarium oxysporum as
filamentous fungi. Isolates S6, S13 and S35 were the most effective
against the tested bacteria and fungi. They had the lowest
Minimum Inhibitory Concentration (MIC) values and showed
the highest and widest spectrum of antibacterial and antifungal activities. Factors
controlling actinomycetes active metabolite(s) productivity were studied.                                                                    

Keywords