Prevalence of Human Papilloma Virus subtypes 52,56,58,59 and 66 among Yemeni Patients with Cervical Cancer

Bensumaidea, Saleh Hussein; Bafakeer, Salim Saeed; Abd El Aziz, Mohammed Siddig; Alshammari, Fawaz D.; Ahmed, Hussain Gadel Karim

doi:10.21608/eajbsg.2014.16495

Prevalence of Human Papilloma Virus subtypes 52,56,58,59 and 66 among Yemeni Patients with Cervical Cancer

Document Type : Original Article

Authors

¹ Department of Histopathology and Cytology, Faculty of Medical Laboratory Science, Sudan University for Science and Technology, Sudan

² Department of Pathology, College of Medicine, Hadhramout University of Science and Technology, Yemen

³ Department of Medical Laboratory, College of applied Medical Science, University of Hail.

⁴ Department of Pathology, College of Medicine, Molecular Diagnostics and Personalized Therapeutics Unit, University of Hail, KSA; Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan

10.21608/eajbsg.2014.16495

Abstract

Background: Knowledge of high risk Human Papilloma Virus (HPV) subtypes might be helpful for development of strategies for decreasing the burden of risk of cervical cancer. Therefore, the aim of this study was to screen for some HR-HPV subtypes that are less common in many regions.
Methodology: A total of 150tissue samples obtained from patients with cervical cancer in addition to 50 tissue samples obtained from patients with benign cervical lesions, were investigated for the presence of HPV subtypes 52,56,58,59 and 66 by Polymerase Chain Reaction (PCR).
Results: The prevalence of HPV subtypes 52,56,58,59, and 66, among cases was 0.6%, 0%, 4%, 3.3% and 0% respectively.
Conclusion: HPV subtypes 58 and 59 have a considerable contribution to etiology of cervical cancer in Yemen that requires further consideration.

Keywords