Effect of Zinc Ferrite Nanoparticles with Antibiotics on klebsiella pneumoniae isolated from Infection Wound

Hassen, Faesal G.; Hassen, Arwa T.

doi:10.21608/eajbsg.2023.331275

Effect of Zinc Ferrite Nanoparticles with Antibiotics on klebsiella pneumoniae isolated from Infection Wound

Document Type : Original Article

Authors

Department of Pathological Analysis, College of Applied Sciences,Samarra University

10.21608/eajbsg.2023.331275

Abstract

It is known that inflammation after surgical operations is a big problem for many people. The person is often exposed to a bacterial infection during the operation and during his visit to the hospital to change the surgical dressing or during the need to stay in the hospital to perform a surgery as an infection inside the hospital. This study included the collection of 200 samples from the site of inflammation using a cotton swab for both sexes and different ages. The isolates were diagnosed based on the phenotypic characteristics of K.Pneumoniae bacteria, conducting biochemical tests for the isolates, and comparing the results with approved references to know the genus and type of bacteria. The diagnosis was confirmed by using the API-20 system. The results showed that 50 isolates belonging to the genus K.Pneumoniae bacteria, with a rate of 25% of the total samples.
Examinations of the anti-inhibitory activity of zinc ferrite nanoparticles ZnFe₂O₄-NPs were carried out on K.pneumoniae bacteria by double dilutions (tubes) with six double concentrations (2,4,8,16,32,64) μ g / ml. The highest inhibition percentage was at a concentration of 64 μ g / ml, with an inhibition rate of 96.5%, and the lowest inhibitory concentration of MIC bacteria was at a concentration of 2 μg / ml.

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